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In patients with early onset of growth hormone deficiency in childhood, the ability to secrete growth hormone should be examined at the end of the growth phase.
This review is not necessary in patients with more than three pituitary hormone deficiencies.
In patients with severe growth hormone deficiency due to a defined genetic cause, due to structural hypothalamic-pituitary abnormalities. Central nervous system or high-dose cerebral radiation therapy.
Or due to growth hormone deficiency following pituitary or hypothalamic disease, or pituitary or hypothalamic involvement.
Action mechanism
Norditropin is a human growth hormone produced by genetic engineering (somatropinum humanum), identical to the hormone extracted from the human pituitary composed of a peptide chain of 191 amino acids.
Growth hormone (GH), also known as somatotropin (or as human growth hormone [hGH or HGH] in its human form), is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in human development. It is a type of mitogen which is specific only to certain kinds of cells.
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Excess
Additionally, these somatotroph adenomas are benign and grow slowly, gradually producing more and more GH. For years, the principal clinical problems are those of GH excess.
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